As with all treatments, some difficulties and problems can be seen in IVF treatment. Although a physician who manages in vitro fertilization is able to overcome some of these difficulties, sometimes the interventions that physicians can do are very limited.

Cancellation of treatment

Treatment may be canceled due to inadequacy of follicle development and inadequate response to IVF treatment. It is much more rare, but sometimes the patient’s excessive response to the drug may also require treatment to be canceled.

Lack of eggs in IVF treatment

Especially in older women and / or women with low ovarian reserve, although the follicles reach an adequate size, no eggs may be found during egg collection.

Lack of sperm in IVF treatment

On average 40% of TESE patients cannot have sperm, and treatment has to be canceled.

Lack of fertilization in IVF treatment

Although eggs and sperm are normal, some eggs may not fertilize. Average egg fertilization rate is 70-80%.

Difficult transfer of embryo

In some cases, transfer can be very difficult due to the anatomical structure of the female genital organs. In such cases, the chance of pregnancy decreases considerably.

Bleeding before pregnancy test

Although the chance of pregnancy decreases in patients with bleeding before the test day, it does not mean that there is no pregnancy.

Overexcitation of ovaries (OHSS)

OHSS is the most important complication of IVF treatment. It usually occurs in women with polycystic ovary syndrome. Excessive response to the drugs used to stimulate the ovaries may lead to the syndrome. There is a fine line between overexcitation and the number of eggs that are acceptable during ovarian stimulation. Dose adjustment may not always be possible. In the event of overexcitation, the ovarian stimulant is prevented from overdosing as a result of reducing the dose of the ovarian stimulant drugs and, if necessary, not administering the drug for a day or more. Syndrome does not occur in cases where hCG injection (egg cracking needle) is not given prior to egg collection.

The development of this syndrome may be prevented or less severe by choosing different treatment protocols appropriate to the patient. The development of pregnancy causes the syndrome to develop more severely. It can even create a life-threatening risk for the mother if the condition is severe. This syndrome regresses in non-pregnant women in a short time. However, in pregnant women, the process may be prolonged by triggering pregnancy hormone.