Artificial uterus (co-culture)

Artificial uterus (co-culture)

The tissue placed inside the uterus is called an artificial uterus. Women who cannot conceive in normal ways try to become pregnant using this method.

Artificial Uterus for IVF Treatment

Intrauterine tissue culture is not applied to all patients in vitro fertilization. It is suitable for patients over 40 years of age, in patients with previous failed IVF trials, in couples with slow or poor development of embryos, in patients with high FSH and in patients with low response to drug treatment.

Intrauterine tissue culture is not applied to all patients in vitro fertilization. It is suitable for patients over 40 years of age, in patients with previous failures.

On the 21st day of the menstruation, a small tissue sample taken from the uterus is separated under laboratory conditions, culture medium is formed with the patient’s own blood serum and the necessary cells are multiplied and frozen. Then the patient is taken to IVF treatment. When the eggs are collected, frozen samples are thawed and an artificial intrauterine tissue called co-culture is created.

After in vitro fertilization and fertilization, embryos are grown in this tissue until transfer. Jaundice, AIDS and other risky conditions are ruled out since the woman’s own intrauterine (endometrium) cells are used during this application. Endometrial cells do not interfere with embryo development, ensure their development and increase the chances of growth.

In the co – culture environment, the relationship between embryo and intrauterine tissue develops in a similar way to the body and the embryo and the mother ‘s uterine wall cells are introduced and used to each other. Growth factors and nutrients contained in co-culture fluids, which are rich in proteins and factors necessary for embryo development, support embryo development. In addition, the antioxidants formed in the environment remove residues that may be harmful to the embryo from the environment of the embryo.

These proteins and growth factors are very limited in the artificial culture medium, ready for use in vitro. Therefore, co-culture is an alternative to ready-to-use culture fluids in patients who fail to treat recurrent IVF. The preparation of endometrial co-culture requires an intensive workforce and technical infrastructure and requires specially trained personnel.

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